Being an April Fool means being gullible. There’s certainly an argument to be said that having childlike innocence and trust is a liability in dealing with other human beings. But overall, I think the benefits of being an April Fool outweigh the drawbacks.
Cultivate trust. Believe the people you love.
The qualities that make April Fools susceptible to practical jokes also makes them susceptible to beauty, to art, to love.
Don’t take advantage of April Fools, but cultivate your inner April Fool.